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Fig. 2 | Molecular Brain

Fig. 2

From: Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics

Fig. 2

The laminar structure of the retina was similar between WT and APLP2-KO except for the OPL. a SD-OCT sections revealed no gross alteration of the young and adult retinas. b Ex vivo histology of 80 nm-thick resin retina sections showed an irregular OPL (arrows) in the young and adult APLP2-KO. c Thicknesses of major retinal layers in WT and APLP2-KO young and adult retinas determined using Visilog 6.4 version software (Noesis). Mean ± s.e.m., N = 4 mice per genotype. d Electron micrographs showed an irregular thickness and pathological aspect of the OPL in young and adult APLP2-KO

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Molecular Brain

ISSN: 1756-6606