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Fig. 2 | Molecular Brain

Fig. 2

From: A1 adenosine receptor attenuates intracerebral hemorrhage-induced secondary brain injury in rats by activating the P38-MAPKAP2-Hsp27 pathway

Fig. 2

Effects of A1AR on ICH-induced SBI. a Western blot analysis showing expression of A1AR, active caspase-3, and albumin in the sham, ICH, ICH + R-PIA, and ICH + 8-PT groups at 48 h after ICH onsets. b Quantification of the results in panel A. The mean values of the protein levels in the sham group were normalized to 1.0. *p < 0.05 for the ICH group versus the sham group, #p < 0.05 for the ICH + R-PIA group versus the ICH group, & p < 0.05 for the ICH + 8-PT group versus the ICH group. c TUNEL staining showing effects of A1AR on SBI at 48 h after ICH onsets. Representative images from sham, ICH, ICH + DMSO, ICH + R-PIA, and ICH + 8-PT groups. Each group was subjected to ICH except for the sham group. Scale bar = 50 μm. d The percentage of TUNEL-positive neurons. *p < 0.05 for the ICH group versus the sham group, #p < 0.05 for the ICH + R-PIA group versus the ICH group, & p < 0.05 for the ICH + 8-PT group versus the ICH group

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Molecular Brain

ISSN: 1756-6606