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Fig. 2 | Molecular Brain

Fig. 2

From: Heantos-4, a natural plant extract used in the treatment of drug addiction, modulates T-type calcium channels and thalamocortical burst-firing

Fig. 2

Voltage-dependent effects of Heantos of T-type calcium channel isoforms. a Representative current traces to various test potentials from a holding potential of −110 mV before (black) and after (grey) Heantos (0.1 mg/ml). b Current density-voltage relationship, c voltage dependence of activation, d activation kinetics and e inactivation kinetics for the effect of Heantos (0.1 mg/ml) on CaV3.1, CaV3.2 and CaV3.3 T-type calcium channel currents (n = 5 per isoform)

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