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Table 1 Summary of GO-based microarray analysis

From: Treatment of intermittent hypoxia increases phosphorylated tau in the hippocampus via biological processes common to aging

Experimental models

GO term clusters

GSE #

Comparison

Implication

A

B

C

E

IH5D vs. Ctrl

IH5D

(6/11)

(5/5)

(18/20)

(11/11)

62385

IH28D vs. Ctrl28

IH28D

(6/11)

(5/5)

(10/20)

(11/11)

12 m vs. Ctrl

Aging

(11/11)

(5/5)

(18/20)

(11/11)

18 m vs. 3.5 m

Aging

(0/11)

(1/5)

(8/20)

(0/11)

29075

KA vs. Saline

KA treatment

(4/11)

(5/5)

(20/20)

(11/11)

60772

Dicer KO vs. Ctrl

Dicer ablation

(6/11)

(0/5)

(8/20)

(0/11)

61937

Dicer KO vs. Ctrl

Dicer ablation

(1/11)

(0/5)

(8/20)

(8/11)

23847

Glud1 Tg vs. Ctrl

Moderate glutamate excess

(0/11)

(5/5)

(16/20)

(1/11)

11419

  1. Shown are alteration patterns of GO term clusters A, B, C and E in each experimental model. An up arrow (a down arrow) was indicated if 50% or more of the GOs belonging to the cluster have a p value of 0.01 or less in the direction of increasing (decreasing) gene expression, respectively. Each arrow was indicated with a description such as “16/20”, which was stated that 16 of the 20 total numbers made significant fluctuations. In addition, we used a right-pointing arrow to represent “8/20”. All the rest parts of the table were indicated using hyphens. Comparisons and their biological implications are shown in the two rows on the left. A corresponding GSE # of each data is shown at the rightmost row. Our experimental data have been deposited as GSE62385. Ctrl, control; IH5D, exposed to IHT for 5 days; IH28D, exposed to IHT for 28 days; m, months; KA, kainic acid; KO, knock out, Glud1, glutamate dehydrogenase 1; Tg, transgenic