Fig. 3
From: The neurotoxicity of amyloid β-protein oligomers is reversible in a primary neuron model
Effects of Aβ-O treatment and removal on aberrant cleavage of tau. a Primary neurons grown on coverslips were treated as in Fig. 1, followed by double-immunofluorescence staining with anti-cleaved tau (green) and anti-CREB (red) antibodies. Scale bar = 20 μm. b The percentage of all CREB-positive cells positive for cleaved tau was calculated as described in Methods and graphed. Data represent means ± SEM from three separate experiments. *p < 0.05, compared with control. #p < 0.05, compared with Aβ-O-treated cells