The ERM protein Moesin is essential for neuronal morphogenesis and long-term memory in Drosophila

Table 2 Summary of LPTC defects resulting from elav-GAL4 driven expression of UAS-Moe constructs

	Control	MoeKD	Myc-Moe	Myc-MoeT559D
Number^a	19	21	15	18
Abnormal morphology^b (%)	0	76	40	22
Increased intensity of Lifeact in VS1 dendritic protrusions^c (%)	0	n/a^d	0	44

^aThe percentage of each lobe phenotype was calculated from the total number of brain hemispheres analyzed for each genotype (n). ^bBrain hemispheres were scored as “abnormal morphology” when one or more branches were missing, reduced in length or thinner than controls. ^cThe relative intensity of Lifeact in the dendritic protrusions was visually compared to that of the branch. If the protusion/branch intensity appeared higher than control brains, it was scored as “increased”. ^dMoeKD was unable to be scored due to the severe branching defects. All analyses were performed by a blinded observer

ISSN: 1756-6606