Fig. 5
ZBD-2-induced reversal of the decreased expression of GABAA receptors in the PPD mice. a The representative Western blot analysises of GABAergic proteins are displayed in the BLA. b, c GABAA-α2 and GABAA-γ2 levels were decreased in the BLA of PPD mice. ZBD-2 administration reversed the downregulation of GABAA-α2 and GABAA-γ2 expression in the PPD mice. The effects of ZBD-2 were abolished by PK11195. There were no differences between ZBD-2 and fluoxetine treatment groups. n = 5 in each group. *p < 0.05, **p < 0.01 compared with the control; #p < 0.05, ##p < 0.01 compared with the PPD model; $p < 0.05, $$p < 0.01 compared with the ZBD-2 (1.5 mg/kg) group. PK: PK11195