Fig. 3
From: DNMT1 regulates expression of MHC class I in post-mitotic neurons
Knockdown of DNMT1 decrease markers of synaptic function in post-mitotic mouse CGNs. Shown is the fold change in gene expression of DNMT1 (a), H2-D1/L (b), synaptophysin (c) and VGlut1 (d) following 72 h siRNA treatment of CGN cultures. Baseline indicate gene expression level in CGNs treated with non-targeting siRNA. Bars represent mean +/− S.E.M., N = 5 from two independent experiments. Stars illustrate effects that are significantly different from non-targeting siRNA group. * p < 0.05, ** p < 0.01, multiplicity corrected p-values in a One-Way ANOVA with Dunnett’s post hoc test