Fig. 3

Temperature sensitivity of isolated leak K⁺ currents in acutely dissociated small-sized DRG neurons of rats. a Sample traces of isolated leak K⁺ currents recorded from an acutely dissociated small-sized DRG neuron at room temperature of 22 °C (top), cool temperature of 14 °C (middle), and warm temperature of 30 °C (bottom). The leak currents were recorded at the voltage step from − 74 mV to 34 mV. b I-V curves of the temperature sensitive leak K⁺ currents illustrated in (a) (n = 32). c Sample traces of leak K⁺ currents recorded from an acutely dissociated small-sized DRG neurons at room temperature of 22 °C (top) and warm temperature of 30 °C (Bottom). Cool temperature of 14 °C evoked a conductance (Middle) which was consistent with TRPM8 activation. Currents were recorded at the voltage step from − 74 mV to 34 mV. d I-V curves of leak K⁺ currents at 22 °C and 30 °C as well as conductance at 14 °C illustrated in (c) (n = 10). Data represent Mean ± SEM in (b) and (d)