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Fig. 5 | Molecular Brain

Fig. 5

From: Characterization of temperature-sensitive leak K+ currents and expression of TRAAK, TREK-1, and TREK2 channels in dorsal root ganglion neurons of rats

Fig. 5

Effects of norfluoxetine and PGF2α on isolated leak K+ currents at different temperatures in acutely dissociated small-sized DRG neurons of rats. a Summary data of the amplitudes of isolated leak K+ currents at 14 °C, 22 °C and 30 °C in the absence (control, open bars) and present of 5 μM norfluoxetine (NF, closed bars, n = 7). b Summary data of the normalized amplitudes of isolated leak K+ currents at 14 °C, 22 °C and 30 °C in the absence (control, open bars) and present of 5 μM NF (closed bars, n = 7). c Summary data of amplitudes of isolated leak K+ currents at 14 °C, 22 °C and 30 °C in the absence (control, open bars) and present of 1 μM PGE2α (closed bars, n = 8) d Summary data of normalized amplitudes of isolated leak K+ currents at 14 °C, 22 °C and 30 °C in the absence (control, open bars) and present of 1 μM PGE2α (closed bars, n = 8). In all recordings, leak K+ currents were induced by voltage steps from − 74 mV to 34 mV. Data represent Mean ± SEM, *p < 0.05, **p < 0.01, comparing between control and in the presence of the testing compounds, two-way ANOVA

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