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Fig. 4 | Molecular Brain

Fig. 4

From: Exposure to mild blast forces induces neuropathological effects, neurophysiological deficits and biochemical changes

Fig. 4

Induction of microvascular damage after mild bTBI. a and b Microvascular damage in rat brain 3 days post-bTBI as indicated by small hemorrhagic focus (arrowhead) in the corpus callosum (a), in conjunction with reactive astrogliosis in the same area (b). c Extravasation of blood plasma in a venule-like microvessel in the deep layer of the cerebral cortex at 3 days post-bTBI are indicated by an arrowhead. d Extravasation of blood plasma in an arteriole-like microvessel in striatum at 3 days post-bTBI. e Immunoreactivity for rat immunoglobulin G (IgG) was detected in the same area as the extravasation of blood plasma in (d). Representative microscope pictures of brain regions stained with H&E (a, c and d), anti-GFAP antibody (b) and anti-rat IgG antibody (e) are shown. Analysis included n = 3 rats for each treatment group. Scale bars: 50 μm (a, b and d); 20 μm (c and e)

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Molecular Brain

ISSN: 1756-6606