Fig. 1

Brain mitochondrial proteins properties, regulation and localization. a Molecular weight distribution of iTRAQ quantified brain mitochondrial proteins, b pI distribution of iTRAQ quantified brain mitochondrial proteins, c Volcano plot of the log₁₀(p-values) as a function of log₂(protein fold change). The statistical significance (p-value in a − log₁₀ scale) is plotted as a function of the protein fold change (in a log₂ scale), d Cellular localization of mitochondrial proteins as determined by gene ontology