Fig. 14
From: Absence of BBSome function leads to astrocyte reactivity in the brain
Loss of or reduced BBS8 protein levels are associated with increased protein levels of reactive astrocyte markers without alteration of protein markers of microglia activation in brains of BBS8-\- mice. Relative levels of protein changes are summarized, and figure shows steady state protein levels on the left, in the center image of a representative total protein stain, and on the right graph of western blot analysis from total brain protein lysate of corresponding control mice, Bbs8flox; Cre+, and Bbs8−/− mice. Data are presented in the graph as relative mean signal intensity (arbitrary units (AU)) + SEM. a wt and BBS8-\- mice (n = 4/genotype, *p < 0.04), **p < 0.002), b) Bbs8flox; Cre- and Bbs8flox; Cre + mice (− = Bbs8flox; Cre- and + = Bbs8flox; Cre + (n > 4/genotype, p > 0.05)