Gene name | SwissProt Accession Number | Protein | Fold up−/down-regulateda | ||
---|---|---|---|---|---|
R18 vs Cont | Glut vs Cont | R18 + Glut vs Glut | |||
Mitochondrial respiration/function | |||||
 Acly | P16638 | ATP-citrate synthase | 1.076 | −2.399 b | 1.659 |
 Aco2 | Q9ER34 | Aconitate hydratase, mitochondrial | −1.028 | −3.435 | 4.285 |
 Atp5a1 | P15999 | ATP synthase subunit alpha, mitochondrial | −1.472 | 1.888 | −2.421 |
 Atp5b | P10719 | ATP synthase subunit beta, mitochondrial | −1.117 | 2.558 | −3.342 |
 Atp5h | P31399 | ATP synthase subunit d, mitochondrial | 1.076 | 2.754 b | −1.836 |
 Atp5o | Q06647 | ATP synthase subunit O, mitochondrial | 1.406 | 2.032 b | −1.644 |
 Cat | P04762 | Catalase | −1.555 | 1.138 | −1.659 b |
 Cox4i1 | P10888 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | −1.259 | 2.070 | −2.704 |
 Idh1 | P41562 | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.066 | 1.459 | −1.486 |
 Mdh2 | P04636 | Malate dehydrogenase, mitochondrial | −1.247 | 2.355 | −2.535 |
 Ndufs1 | Q66HF1 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | 1.294 | 2.443 | −5.249 |
 Uqcrc2 | P32551 | Cytochrome b-c1 complex subunit 2, mitochondrial | −1.247 | 1.888 | −2.704 |
Proteasome & Protein synthesis | |||||
 Asns | P49088 | Asparagine synthetase [glutamine-hydrolyzing] | 2.089 | 2.228 | 2.421 b |
 Cct2 | Q5XIM9 | T-complex protein 1 subunit beta | 1.106 | −3.802 | 3.631 |
 Cct3 | Q6P502 | T-complex protein 1 subunit gamma | −1.158 | −4.787 | 4.207 |
 Cct4 | Q7TPB1 | T-complex protein 1 subunit delta | 1.127 | −3.944 | 3.499 |
 Cct5 | Q68FQ0 | T-complex protein 1 subunit epsilon | 1.096 | −2.269 | 2.291 |
 Psmc1 | P62193 | 26S protease regulatory subunit 4 | −1.419 | −22.67 | 18.197 |
Axonal growth/Neuronal differentiation/Cytoskeletal arrangement | |||||
 Actr2 | Q5M7U6 | Actin-related protein 2 | −1.355 | − 1.271 | − 1.459 b |
 Ap2m1 | P84092 | AP-2 complex subunit mu | 1.271 | −5.394 | 6.855 |
 Armc10 | B1WBW4 | Armadillo repeat-containing protein 10 | −1.294 | −6.667 | 2.070 |
 Baiap2 | Q6GMN2 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | −1.331 | −90.09 | 99.083 |
 Basp1 | Q05175 | Brain acid soluble protein 1 | 1.343 | 1.614 | −1.270 |
 Cntn1 | Q63198 | Contactin-1 | −1.117 | 1.977 | −1.836 |
 Cttn | Q66HL2 | Src substrate cortactin | 1.117 | −5.345 b | 3.251 |
 Dcx | Q9ESI7 | Neuronal migration protein doublecortin | 1.000 | −6.139 | 6.026 |
 Dnm1 | P21575 | Dynamin-1 | −2.148 | −4.093 | 3.076 |
 Dpysl2 | P47942 | Dihydropyrimidinase-related protein 2 | −1.225 | 1.723 | −1.690 |
 Dync1h1 | P38650 | Cytoplasmic dynein 1 heavy chain 1 | −1.087 | −8.873 | 8.472 |
 Fabp7 | P55051 | Fatty acid-binding protein, brain | −1.028 | 4.406 b | −4.207 |
 Fyn | Q62844 | Tyrosine-protein kinase Fyn | 1.117 | −2.489 | 2.754 b |
 Gdi1 | P50398 | Rab GDP dissociation inhibitor alpha | −1.419 | 1.820 | −2.965 |
 Gfap | P47819 | Glial fibrillary acidic protein | 1.4322 | 1.906 b | −1.159 |
 Kif21b | F1M5N7 | Kinesin-like protein KIF21B | −1.282 | −17.857 | 16.444 |
 Krt1 | Q6IMF3 | Keratin, type II cytoskeletal | −4.055 b | −1.236 | −6.485 |
 Krt10 | Q6IFW6 | Keratin, type I cytoskeletal 10 | −2.168 | −1.722 | −16.892 b |
 Map2 | P15146 | Microtubule-associated protein 2 | 1.138 | −8.628 | 11.482 |
 Map4 | Q5M7W5 | Microtubule-associated protein 4 | −2.884 | −4.488 | 4.169 |
 Mapt | P19332 | Microtubule-associated protein tau | 1.077 | −7.179 | 7.379 |
 Myh10 | Q9JLT0 | Myosin-10 | −1.459 | −2.466 | 2.228 |
 Ncam1 | P13596 | Neural cell adhesion molecule 1 | −1.180 | 2.831 | −4.093 |
 Pa2 g4 | Q6AYD3 | Proliferation-associated protein 2G4 | 1.202 | −2.188 | 2.489 b |
 Pak3 | Q62829 | Serine/threonine-protein kinase PAK 3 | −2.208 | −4.365 | 5.754 b |
 bPebp1 | P31044 | Phosphatidylethanolamine-binding protein 1 | 1.5276 | 2.780 b | −2.128 |
 Rala | P63322 | Ras-related protein Ral-A | −1.236 | 2.704 b | −1.690 |
 Rtn4 | Q9JK11 | Reticulon-4 | 1.107 | −2.148 | 2.679 |
 Tpm4 | P09495 | Tropomyosin alpha-4 chain | −1.097 | −2.270 | 1.738 b |
 Tuba4a | Q5XIF6 | Tubulin alpha-4A chain | 1.086 | −2.679 b | 2.535 |
 Tubb5 | P69897 | Tubulin beta-5 chain | −1.038 | −18.018 | 16.444 |
Vesicular/Transmembrane trafficking | |||||
 Actn4 | Q9QXQ0 | Alpha-actinin-4 | −1.294 | 1.906 b | −1.381 |
 Actr1a | P85515 | Alpha-centractin | −1.738 | −3.565 b | 2.148 |
 Ap2a2 | P18484 | AP-2 complex subunit alpha-2 | 1.159 | −2.582 | 3.698 b |
 Atp1a3 | P06687 | Sodium/potassium-transporting ATPase subunit alpha-3 | −2.128 | 1.660 | −2.355 |
 Cadps | Q62717 | Calcium-dependent secretion activator 1 | −1.486 | −11.481 | 6.194 |
 Camk2a | P11275 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | −1.419 | −6.667 | 6.918 |
 Cask | Q62915 | Peripheral plasma membrane protein CASK | 1.514 | 1.306 | −1.888 b |
 Dpysl5 | Q9JHU0 | Dihydropyrimidinase-related protein 5 | −1.180 | 1.213 | −1.459 b |
 Klc1 | P37285 | Kinesin light chain 1 | 1.107 | −6.024 b | 5.058 |
 Nsf | Q9QUL6 | Vesicle-fusing ATPase | −1.117 | −5.807 | 4.656 |
 Prkar2b | P12369 | cAMP-dependent protein kinase type II-beta regulatory subunit | −1.472 | −3.105 | 1.754 |
 Stx1b | P61265 | Syntaxin-1B | 1.225 | 1.600 | −1.419 |
 Stxbp1 | P61765 | Syntaxin-binding protein 1 | −1.107 | 1.600 | −2.466 |
 Syn1 | P09951 | Synapsin-1 | −1.786 | −3.597 b | 3.3113 |
ER proteostasis/Protein modification | |||||
 Calr | P18418 | Calreticulin | 1.419 | 1.871 | −1.570 |
 Ddost | Q641Y0 | Oligosaccharyl transferase 48 kDa subunit | −1.500 | 2.466 | −2.938 |
 Erp29 | P52555 | Endoplasmic reticulum resident protein 29 | −1.067 | 2.168 b | −3.163 |
 Hsp90aa1 | P82995 | Heat shock protein HSP 90-alpha | 1.038 | 1.282 | −1.446 b |
 Hspa5 | P06761 | 78 kDa glucose-regulated protein | 1.038 | 2.014 | −1.542 |
 Hspa8 | P63018 | Heat shock cognate 71 kDa protein | 1.259 | −2.208 | 2.559 b |
 Hspa9 | P48721 | Stress-70 protein, mitochondrial | 1.159 | −6.083 | 8.318 |
 Hspd1 | P63039 | 60 kDa heat shock protein, mitochondrial | 1.107 | 1.486 | −1.556 |
 Pdia3 | P11598 | Protein disulfide-isomerase A3 | −1.600 | 1.614 | −1.995 |
 Phb | P67779 | Prohibitin | −1.213 | 1.644 | −2.535 |
 Phb2 | Q5XIH7 | Prohibitin-2 | −1.047 | 3.837 | −2.992 |
 Por | P00388 | NADPH--cytochrome P450 reductase | −1.107 | −1.038 | 1.343 b |
 Tcp1 | P28480 | T-complex protein 1 subunit alpha | −1.472 | −3.597 b | 2.911 |
 Uba1 | Q5U300 | Ubiquitin-like modifier-activating enzyme 1 | −1.107 | −5.105 | 4.406 |
Glycolysis & Carbohydrate metabolism | |||||
 Alb | P02770 | Serum albumin | −1.570 | 1.722 | −5.701 |
 Aldoa | P05065 | Fructose-bisphosphate aldolase A | −1.660 | 1.629 | −2.355 |
 Eno1 | P04764 | Alpha-enolase | 1.107 | 2.911 | −1.706 |
 Gapdh | P04797 | Glyceraldehyde-3-phosphate dehydrogenase | −1.028 | −11.700 | 10.280 |
 Gpi | Q6P6V0 | Glucose-6-phosphate isomerase | −1.318 | 1.754 | −3.435 |
 Hk1 | P05708 | Hexokinase-1 | 1.138 | 2.051 b | −1.888 |
 Ldha | P04642 | L-lactate dehydrogenase A chain | −1.786 | 1.028 | −1.675 b |
 Pkm | P11980 | Pyruvate kinase PKM | −1.009 | 1.787 | −1.941 |
 Taldo1 | Q9EQS0 | Transaldolase | 1.259 | −1.837 | 2.109 |
Mitochondrial fatty acid synthesis | |||||
 Acat1 | P17764 | Acetyl-CoA acetyltransferase, mitochondrial | 1.159 | 2.377 | −1.500 |
 Bdh1 | P29147 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial | −1.213 | −5.970 | 4.246 |
 Fasn | P12785 | Fatty acid synthase | −1.117 | −3.311 | 2.704 |
 Got2 | P00507 | Aspartate aminotransferase, mitochondrial | −1.923 | 1.213 | −2.109 b |
Ribosome components/RNA trafficking & processing | |||||
 Aars | P50475 | Alanine--tRNA ligase, cytoplasmic | −1.556 | −5.495 | 4.699 |
 C1qbp | O35796 | ASF/SF2-associated protein p32 | 1.213 | 1.600 b | −1.888 |
 Ddx1 | Q641Y8 | ATP-dependent RNA helicase DDX1 | −1.148 | −11.173 | 4.286 |
 Eef1a1 | P62630 | Elongation factor 1-alpha 1 | −1.225 | −5.444 | 4.529 |
 Eef2 | P05197 | Elongation factor 2 | −1.202 | −4.131 | 3.048 |
 Eif4a2 | Q5RKI1 | Eukaryotic initiation factor 4A-II | −1.057 | −3.945 | 3.02 |
 Eif5a | Q3T1J1 | Eukaryotic translation initiation factor 5A-1 | 1.514 | −6.983 | 9.638 |
 Elavl2 | Q8CH84 | ELAV-like protein 2 | −1.107 | −4.405 | 5.598 b |
 Hnrnpa1 | P04256 | Heterogeneous nuclear ribonucleoprotein A1 | −1.076 | −9.911 | 9.462 |
 Hnrnpa2b1 | A7VJC2 | Heterogeneous nuclear ribonucleoproteins A2/B1 | 1.318 | −4.325 | 6.138 |
 Hnrnpa3 | Q6URK4 | Heterogeneous nuclear ribonucleoprotein A3 | 1.191 | −3.311 | 4.920 |
 Hnrnpd | Q9JJ54 | Heterogeneous nuclear ribonucleoprotein D0 | 1.202 | −5.495 | 6.252 |
 Hnrnpk | P61980 | Heterogeneous nuclear ribonucleoprotein K | −1.057 | −8.091 | 8.872 |
 Hnrnpl | F1LQ48 | Heterogeneous nuclear ribonucleoprotein L | −1.028 | −2.729 | 4.207 b |
 Khsrp | Q99PF5 | Far upstream element-binding protein 2 | 1.556 | −3.908 | 8.017 b |
 Matr3 | P43244 | Matrin-3 | −1.500 | −3.373 b | 3.945 |
 Rpl7 | P05426 | 60S ribosomal protein L7 | 1.225 | −2.109 | 2.188 b |
 Rpl13 | P41123 | 60S ribosomal protein L13 | −1.057 | −2.377 | 2.754 b |
 Rplp0 | P19945 | 60S acidic ribosomal protein P0 | 1.486 b | −1.191 | −1.076 |
 Rps24 | P62850 | 40S ribosomal protein S24 | 1.854 | −5.754 | 14.06 b |
 Rps27 | Q71TY3 | 40S ribosomal protein S27 | −1.102 | −18.18 b | 5.058 |
 Yars | Q4KM49 | Tyrosine--tRNA ligase, cytoplasmic | −1.225 | −4.656 | 3.342 |
Calcium transport and signalling | |||||
 Vdac1 | Q9Z2L0 | Voltage-dependent anion-selective channel protein 1 | −1.419 | 2.466 | −2.938 |
 Cacna2d1 | P54290 | Voltage-dependent calcium channel subunit alpha-2/delta-1 | 1.306 | 4.207 | −4.018 |
 Gnao1 | P59215 | Guanine nucleotide-binding protein G(o) subunit alpha | −1.148 | −5.152 | 3.802 |
 Letm1 | Q5XIN6 | LETM1 and EF-hand domain-containing protein 1, mitochondrial | −3.020 | 1.459 b | −1.236 |
 Nudt3 | Q566C7 | Diphosphoinositol polyphosphate phosphohydrolase 1 | 1.459 b | 1.282 | 1.117 |
 Ywhaq | P68255 | 14–3-3 protein theta | −1.087 | 1.355 | −1.615 |
Miscellaneous | |||||
 Ak1 | P39069 | Adenylate kinase isoenzyme 1 (Cellular energy homeostasis) | 1.009 | −2.938 | 4.325 |
 Atic | O35567 | Bifunctional purine biosynthesis protein PURH (Purine biosynthesis) | 1.038 | 1.923 | −2.630 b |
 Dnm1l | O35303 | Dynamin-1-like protein (Mitochondrial fission) | −1.820 | −7.519 b | 5.297 |
 Hist1h4b | P62804 | Histone H4 (Transcription regulation) | 1.754 | −3.802 | 7.516 b |