Fig. 1
From: miR-212-5p attenuates ferroptotic neuronal death after traumatic brain injury by targeting Ptgs2
The concentration of MDA and Fe2+ and the mRNA levels of ferroptosis-related molecules following CCI. MDA (a) and Fe2+ (b) levels in the ipsilateral cortex at 6 h, 12 h, 24 h, 48 h, and 72 h after CCI (n = 6 for each group). Quantitative RT-PCR showing the relative expression levels of Gpx4 (c), Acsl4 (d), Slc7a11 (e), Nox2 (f), Sat1 (g) in the cortex at the indicated times after injury (n = 9 for each group). Data are expressed as mean ± SEM. Data were analyzed using the student’s t-test. *p < 0.05, **p < 0.01, ***p < 0.001. MDA, malondialdehyde; CCI, controlled cortical impact; Fe2+, ferrous ion