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Fig. 8 | Molecular Brain

Fig. 8

From: Silencing of microRNA-146a alleviates the neural damage in temporal lobe epilepsy by down-regulating Notch-1

Fig. 8

The expression of Notch-1, Hes-1 and caspase-9 in hippocampus detected by quantitative real-time PCR (qRT-PCR) and/or Western blot (N = 8) was performed at 3 days after the injection. Model, temporal lobe epilepsy (TLE) rats; Control, normal rats; microRNA-146a (miRNA-146a), TLE rats transfected with miRNA-146a siRNA; miRNA-146a negative control (miRNA-146a NC), TLE rats transfected with miRNA-146a NC. a the expression of Notch-1 detected by qRT-PCR (mRNA level); b) the expression of Notch-1, Hes-1 and caspase-9 detected by Western blot (protein level). *, P < 0.05 vs. Control group; **, P < 0.01 vs. Control group; #, P < 0.05 vs. Model group

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Molecular Brain

ISSN: 1756-6606