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Fig. 2 | Molecular Brain

Fig. 2

From: Cortical potentiation induced by calcitonin gene-related peptide (CGRP) in the insular cortex of adult mice

Fig. 2

The potentiation induced by CGRP was NMDA receptor independent. a An NMDA receptor antagonist, AP5 (50 μM), did not affect the CGRP induced potentiation. Left: a time line plot of one representative sample. Right: sample traces showed the increased of the amplitude during the application of CGRP (10 nM) and washout period. b Left: the pooled data illustrated the time course of the effect of CGRP (10 nM) in the IC. Right: summarized data showed the amplitude significantly increased during the application of CGRP and washout period when compared with baseline (n = 8 neurons/5 mice). **p < 0.01 compared with baseline, error bars indicated SEM

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