Skip to main content

Advertisement

Table 1 Assessment of viral spread from WT-VSV and Mutant-VSV injections into the VTA

From: A mutant vesicular stomatitis virus with reduced cytotoxicity and enhanced anterograde trans-synaptic efficiency

Brain regionWT-VSVMutant-VSV
3 DPI5 DPI3 DPI5 DPI10 DPI
AON++++++++
LS++++++++
ACB (NAc)+++++++++
CP++++++++
OT++++
BST+++++++++
Habenula++++++++++
Amygdala++++++
DR+++++++
PIR++++
PFC+
ACA++
MO++
SC++
SOC++
  1. The absence or presence of labeling was indicated by (−) and (+), respectively. The extent of labeling was indicated with the number of (+). Results showed that with the reduced toxicity and extended animal survival, more connected downstream networks were labeled by the Mutant-VSV compared with the WT-VSV