Table 4 The enriched pathways for the overlapped genes between burden test and SKAT-O analysis
From: Exome sequencing study revealed novel susceptibility loci in subarachnoid hemorrhage (SAH)
Pathways | Genes |
|---|---|
Adherens_junction | TJP1 PTPRM |
Angiogenesis | FGFR2 UNC5B NOTCH3 FGFR4 FLT4 |
Apelin_signaling_pathway | NOTCH3 ADCY8 |
Cell_cycle_Role_of_SCF_complex_in_cell_cycle_regulation | FZR1 MAPK8 |
Degradation_of_the_extracellular_matrix | FBN3 ADAMTS18 NCAM1 NTN4 |
LAMB2 LAMB1 CAPN1 COL20A1 FBLN2 | |
COL14A1 ITGA2 NCAN P4HA2 | |
Development_TGF-beta_receptor_signaling | FZR1 |
Elastic_fibre_formation | FBN3 FBLN2 |
Endochondral_Ossification | RUNX2 |
ERK_signaling | MYH1 TCF3 FBN3 ECM2 FGFR2 PRKCQ RPS6KA1 FLT4 |
TCF19 LAMB2 LAMB1 CAPN1 COL20A1 RASGRP1 | |
NOTCH3 ADCY8 ARHGEF16 CDH12 CDH19 COL14A1 FGFR4 | |
IL12RB1 ITGA2 MAPK8 NCAN NTRK3 PLCD4 ARHGEF2 | |
HTLV-I_infection | TCF3 POLE ADCY8 CRTC3 HLA-DPA1 MAPK8 |
Integrin_Pathway | MYH1 FBN3 ECM2 PRKCQ LAMB2 LAMB1 CAPN1 |
COL20A1 ADCY8 CD36 COL14A1 ITGA2 MAPK8 NCAN | |
PAK_Pathway | MYH1 TCF3 TJP1 FGFR2 NOX4 PRKCQ PTPRH |
TCF19 NOTCH3 FGFR4 FLT4 IL12RB1 | |
MAPK8 NTRK3 PLCD4 PTPN3 PTPRM GPLD1 | |
Sertoli-Sertoli_Cell_Junction_Dynamics | MYH1 TJP1 SAFB ITGA2 MAPK8 RAB17 RAB34 ARHGEF2 |
SMAD_Signaling_Network | PSMB8 PSMD5 |
Smooth_Muscle_Contraction | NULL |
TGF-beta_receptor_signaling_activates_SMADs | MTMR4 |
TGF-beta_receptor_signaling | ZFYVE16 |
TGF-beta_signaling_pathway_KEGG | ID4 INHBA SMAD6 ZFYVE16 |
TGF-beta_Signaling_Pathways | MAPK8 RUNX2 |