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Table 4 The enriched pathways for the overlapped genes between burden test and SKAT-O analysis

From: Exome sequencing study revealed novel susceptibility loci in subarachnoid hemorrhage (SAH)

PathwaysGenes
Adherens_junctionTJP1 PTPRM
AngiogenesisFGFR2 UNC5B NOTCH3 FGFR4 FLT4
Apelin_signaling_pathwayNOTCH3 ADCY8
Cell_cycle_Role_of_SCF_complex_in_cell_cycle_regulationFZR1 MAPK8
Degradation_of_the_extracellular_matrixFBN3 ADAMTS18 NCAM1 NTN4
LAMB2 LAMB1 CAPN1 COL20A1 FBLN2
COL14A1 ITGA2 NCAN P4HA2
Development_TGF-beta_receptor_signalingFZR1
Elastic_fibre_formationFBN3 FBLN2
Endochondral_OssificationRUNX2
ERK_signalingMYH1 TCF3 FBN3 ECM2 FGFR2 PRKCQ RPS6KA1 FLT4
TCF19 LAMB2 LAMB1 CAPN1 COL20A1 RASGRP1
NOTCH3 ADCY8 ARHGEF16 CDH12 CDH19 COL14A1 FGFR4
IL12RB1 ITGA2 MAPK8 NCAN NTRK3 PLCD4 ARHGEF2
HTLV-I_infectionTCF3 POLE ADCY8 CRTC3 HLA-DPA1 MAPK8
Integrin_PathwayMYH1 FBN3 ECM2 PRKCQ LAMB2 LAMB1 CAPN1
COL20A1 ADCY8 CD36 COL14A1 ITGA2 MAPK8 NCAN
PAK_PathwayMYH1 TCF3 TJP1 FGFR2 NOX4 PRKCQ PTPRH
TCF19 NOTCH3 FGFR4 FLT4 IL12RB1
MAPK8 NTRK3 PLCD4 PTPN3 PTPRM GPLD1
Sertoli-Sertoli_Cell_Junction_DynamicsMYH1 TJP1 SAFB ITGA2 MAPK8 RAB17 RAB34 ARHGEF2
SMAD_Signaling_NetworkPSMB8 PSMD5
Smooth_Muscle_ContractionNULL
TGF-beta_receptor_signaling_activates_SMADsMTMR4
TGF-beta_receptor_signalingZFYVE16
TGF-beta_signaling_pathway_KEGGID4 INHBA SMAD6 ZFYVE16
TGF-beta_Signaling_PathwaysMAPK8 RUNX2