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Fig. 2 | Molecular Brain

Fig. 2

From: Intraventricular IL-17A administration activates microglia and alters their localization in the mouse embryo cerebral cortex

Fig. 2

a Representative photographs of Iba1 (upper panel) and CD68 immunostaining (lower panel) after exposure to saline (left) and IL-17A (right). Arrowheads indicate accumulated microglia. LV: lateral ventricle. Scale bar = 100 μm. b Effects of IL-17A administration on microglia. Iba1 microglia in cingulate (medial) and somatosensory (lateral) cortices. IL-17A administration at E14.5 did not change the total number of microglia, but increased their tendency to accumulate in the medial region of the cortex. N = 6 per group, two-way ANOVA, * p < 0.05. c Effects of IL-17A administration on activated microglia. CD68 microglia in cingulate (medial) and somatosensory (lateral) cortices. IL-17A administration at E14.5 increased the number of amoeboid-type microglia especially in the medial region of the cortex. N = 6 per group, two-way ANOVA, * p < 0.05

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Molecular Brain

ISSN: 1756-6606