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Table 1 Results of Western blots normalized to wild-type (WT) or vehicle (VEH)-treated groups. TH tyrosine hydroxylase, VGLUT1 vesicular glutamate transporter 1, GAD67 glutamic acid decarboxylase 67, DAT dopamine transporter, DA dopamine, KO knockout, N.A. not applicable. *p < 0.05, compared to WT or VEH groups; Mann-Whitney test. Values are shown as mean ± SEM

From: Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism

  TH VGLUT1 GAD67 DAT
WT 1.00 ± 0.05 1.00 ± 0.18 1.00 ± 0.10 1.00 ± 0.04
BTBR 0.80 ± 0.04* 1.20 ± 0.05 0.94 ± 0.08 0.72 ± 0.05*
Fmr1-KO 1.20 ± 0.17 1.05 ± 0.12 1.10 ± 0.08 0.64 ± 0.05*
BTBR + VEH 1.00 ± 0.05 N.A. N.A. 1.00 ± 0.05
BTBR + DA 1.20 ± 0.07* N.A. N.A. 1.00 ± 0.06
Fmr1-KO + VEH 1.00 ± 0.05 N.A. N.A. 1.00 ± 0.05
Fmr1-KO + DA 0.71 ± 0.07* N.A. N.A. 1.15 ± 0.23