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Table 2 Total exploration time (seconds) in the object-based attention test (OBAT) and three-chamber social test. VEH vehicle, DA dopamine, N.A. not applicable. Values are shown as mean ± SEM

From: Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism

 

BTBR

Fmr1-KO

OBAT

VEH

DA

VEH

DA

learning

21.51 ± 2.29

18.27 ± 1.22

24.86 ± 5.49

26.56 ± 2.19

test

18.16 ± 2.37

18.54 ± 3.04

17.62 ± 4.66

21.58 ± 2.93

Three-chamber

    

 sociability

70.88 ± 12.28

78.25 ± 10.92

62.00 ± 6.10

62.36 ± 8.25

 social novelty

N.A.

N.A.

47.87 ± 6.42

59.18 ± 4.87

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Molecular Brain

ISSN: 1756-6606