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Table 3 Behavioral assessments in the elevated plus maze test. VEH vehicle, DA dopamine. Values are shown as mean ± SEM

From: Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism

  BTBR Fmr1-KO
VEH DA VEH DA
distance (cm) 816.07 ± 57.81 965.20 ± 112.64 1194.93 ± 126.64 1091.41 ± 76.38
entry (counts)
 center 34.58 ± 3.06 36.42 ± 4.18 37.29 ± 2.29 36.67 ± 3.02
 open 13.08 ± 1.56 12.92 ± 1.61 14.29 ± 1.91 15.22 ± 1.98
 closed 22.92 ± 1.64 25.50 ± 3.02 26.71 ± 1.66 25.00 ± 1.59
time spent (seconds)
 center 48.88 ± 6.77 43.01 ± 4.92 71.37 ± 4.80 68.18 ± 7.86
 open 32.78 ± 6.29 37.67 ± 4.99 52.89 ± 7.88 52.91 ± 9.39
 closed 218.33 ± 11.00 219.32 ± 9.15 175.71 ± 8.19 178.90 ± 10.16
head-dips (seconds) 7.19 ± 2.32 7.74 ± 1.10 24.83 ± 2.54 30.47 ± 4.90