Table 3 Behavioral assessments in the elevated plus maze test. VEH vehicle, DA dopamine. Values are shown as mean ± SEM
BTBR | Fmr1-KO | |||
|---|---|---|---|---|
VEH | DA | VEH | DA | |
distance (cm) | 816.07 ± 57.81 | 965.20 ± 112.64 | 1194.93 ± 126.64 | 1091.41 ± 76.38 |
entry (counts) | ||||
center | 34.58 ± 3.06 | 36.42 ± 4.18 | 37.29 ± 2.29 | 36.67 ± 3.02 |
open | 13.08 ± 1.56 | 12.92 ± 1.61 | 14.29 ± 1.91 | 15.22 ± 1.98 |
closed | 22.92 ± 1.64 | 25.50 ± 3.02 | 26.71 ± 1.66 | 25.00 ± 1.59 |
time spent (seconds) | ||||
center | 48.88 ± 6.77 | 43.01 ± 4.92 | 71.37 ± 4.80 | 68.18 ± 7.86 |
open | 32.78 ± 6.29 | 37.67 ± 4.99 | 52.89 ± 7.88 | 52.91 ± 9.39 |
closed | 218.33 ± 11.00 | 219.32 ± 9.15 | 175.71 ± 8.19 | 178.90 ± 10.16 |
head-dips (seconds) | 7.19 ± 2.32 | 7.74 ± 1.10 | 24.83 ± 2.54 | 30.47 ± 4.90 |