Fig. 4
From: Ketamine normalizes high-gamma power in the anterior cingulate cortex in a rat chronic pain model
Ketamine had a long term effect of inhibition on the high-gamma band power in the ACC in chronic pain state. a Timeline for CFA and ketamine injections. b Example of trial-averaged LFP raw trace, in the chronic pain condition five days after ketamine injection. The panel directly below the raw trace shows trial-averaged time–frequency spectrum, with time 0 denoting the time of pinprick stimulation. c Z-score power in the high-gamma frequency band (60–100 Hz) post CFA injection, two days after ketamine injection, and five days after ketamine injection (p = 0.0140 and p = 0.0322, respectively, One-way ANOVA with Dunnett’s multiple comparisons test). Error bars represent SEM. *p < 0.05