Fig. 4

The effects of the injection of α2AP on spatial memory. a α2AP or saline was intracerebroventricularly injected in 12-week-old C57BL/6J mice after the first day of training in the MWM test. On the second day, mice were repeatedly trained, and then the probe tests were performed 30 min and 1 month later. b The results of the training sessions. The latency to the target in each trial was measured, and the values represent the mean values of 4 trials in each session. c and d The results of the probe tests performed 30 min (c) and 1 month (d) after training. The time in each quadrant was measured. The values represent the mean ± S.E. (saline: n = 8, α2AP: n = 10). Statistical significance was evaluated using an ANOVA with an LSD post-hoc test. **P < 0.01