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Fig. 2 | Molecular Brain

Fig. 2

From: Touchscreen-based location discrimination and paired associate learning tasks detect cognitive impairment at an early stage in an App knock-in mouse model of Alzheimer’s disease

Fig. 2

Impaired associative memory of App-KI mice in the dPAL task. a Diagram represents all possible combinations of stimuli presentation. b Five-day blocks of performance during acquisition of the dPAL task. App -KI mice exhibited significantly worse performance than wild-type mice. †p < 0.05 vs control. *p < 0.05 vs each block in control. c Fold change relative to the first block. A significant difference was observed in block 8, although both groups of mice exhibited significant improvement in the last data point relative to the first data point. †p < 0.05 vs control in block 8. *p < 0.05 vs block 1 in each group. Data are presented as means ± SEM (n = 9–11). Chance performance (50%) is indicated by dashed lines

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