Behavioral tests | Test significance | Significant difference | References |
---|---|---|---|
Y-maze | Short-term memory | Yes (6 months) | Saito et al. [13] |
Place preference and reversal task | Spatial learning and reversal learning | Yes (13–14 months) | Masuda et al. [16] |
Serial reaction time task | Impulsivity and attention | Yes (13–14 months) | |
Place avoidance | Extinction learning | Yes (8–9 months) | |
Delay discounting task | Compulsive behavior | Yes (8–9 months) | |
Novel object recognition | Recognition memory | Not detected (6 months) | Whyte et al. [17] |
Y-maze | Working memory | Not detected (6 months) | |
Morris water maze | Spatial reference memory | Not detected (6 months) | |
Open field | Anxiety | Yes (6 months) | |
Fear conditioning | Fear learning | Not detected (15–18 months) | Sakakibara et al. [14] |
Elevated plus maze | Anxiety-related behavior | Yes (6–18 months) | |
Barnes maze | Spatial memory | Yes (8 months) | |
Spatial reversal learning | Flexibility and impulse control | Not detected (8 months) | |
Morris water maze | Spatial reference memory | Not detected (10–11 months) | Latif-Hernandez et al. [15] |
Cage activity and exploration | Spontaneous activity | Yes (3 and 10 months) | |
Social Preference Social Novelty (SPSN) test | Social memory | Not detected (3, 6, and 10 months) | |
Location discrimination | Pattern separation | Yes (4–5 months) | Present study |
Different object–location paired-associate learning | Paired-associative memory | Yes (4–6 months) | |
Visual discrimination, Reversal learning | Cognitive flexibility | Not detected (4–5 months) | |
Morris water maze | Spatial reference memory | Not detected (6 months) |