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Table 2 Correlation between functional connectivity and DTI or social interaction

From: Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain

DTI or behavior

Functional connectivity

Correlation (R)

P value

FA (CP)

ILA–ACB

− 0.4186

0.0417

RD (CP)

PL–DG

− 0.4104

0.0464

PL–ACB

0.5516

0.0052

PL–CP

0.5419

0.0062

ILA–CA3

− 0.4141

0.0442

ILA–CP

0.4489

0.0278

ILA–ACB

0.5682

0.0038

ORB–CA3

− 0.4169

0.0427

ORB–CP

0.5126

0.0104

ORB–ACB

0.4751

0.0190

FA (fx)

PL–DG

0.4286

0.0367

PL–CA1

0.5045

0.0119

PL–SUB

0.5281

0.0080

PL–BLA

− 0.4092

0.0471

PL–CP

− 0.4796

0.0177

ILA–SUB

0.4670

0.0214

ACB–CP

− 0.4226

0.0397

RD (fx)

PL–CA1

− 0.5085

0.0112

PL–SUB

− 0.4442

0.0297

PL–CP

0.5907

0.0024

PL–ACB

0.5339

0.0072

ILA–SUB

− 0.4218

0.0400

ACB–CP

0.4477

0.0282

Behavior (total contact time)

PL–DG

− 0.5065

0.0116

PL–CA1

− 0.5988

0.0020*

PL–SUB

− 0.6877

0.0002**

PL–BLA

0.5169

0.0097

PL–CP

0.4333

0.0344

ILA–SUB

− 0.5230

0.0077

ORB–BLA

0.5742

0.0033*

CP–SUB

− 0.5240

0.0086

CP–ACB

0.4091

0.0472

ACB–SUB

− 0.4798

0.0177

  1. Pearson’s correlation coefficient (R) and P value for functional connectivity between the indicated brain regions and either FA or RD in the indicated brain regions or total contact time in the reciprocal social interaction test are shown. PL prelimbic cortex, ILA infralimbic cortex, ORB orbitofrontal cortex, DG dentate gyrus, CA1 cornu ammonis 1, SUB subiculum, BLA basolateral amygdala, CP caudoputamen, ACB nucleus accumbens. Uncorrected P values are provided together with asterisks (*P < 0.05, **P < 0.01) indicating significance level after correction by the FDR. Correlation coefficients and statistical values are also provided in Additional file 2: Table S2
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Molecular Brain

ISSN: 1756-6606