Table 1 Subclasses of palmitoylated proteins with different contribution to structural plasticity and enzymes catalyzing palmitoylation cycles

Main regulators of actin cytoskeleton modification

 Cdc42

Cys188, Cys189

ZDHHC3, ZDHHC8

–

[83,84,85,86]

 Rac1

Cys178

ZDHHC3, ZDHHC8

–

[78, 87, 88]

 LIMK1

Cys7, Cys8

–

–

[50]

 δ-catenin

Cys960, Cys961

ZDHHC3, ZDHHC5, ZDHHC20

–

[89, 90]

 N-Ras

Cys184

ZDHHC9

APT1, APT2, ABHD17,

[91,92,93,94]

 H-Ras

Cys181, Cys184

ZDHHC9

APT1, APT2, PPT1, ABHD17B

[92, 94,95,96,97,98,99]

AMPAR and associated scaffold proteins which support and stabilize structural plasticity and indirectly link to actin cytoskeleton

 AMPAR

GluA1-Cys585, Cys811; GluA2-Cys610, Cys836; GluA3-Cys615, Cys841; GluA4-Cys611, Cys817

ZDHHC3

–

[86, 89, 90]

 PSD95

Cys3, Cys5

ZDHHC2, ZDHHC3, ZDHHC7, ZDHHC8, ZDHHC15, ZDHHC17

ABHD17

[66, 76, 91, 96, 100,101,102,103,104,105]

 Ankyrin-G

Cys70

ZDHHC5, ZDHHC8

–

[106,107,108,109]

 ABP-L

Cys11

–

–

[83,84,85, 110, 111]

 AKAP79/150

Cys36, Cys129

ZDHHC2

–

[50, 103,104,105]

Candidate proteins whose palmitoylation may contribute to structural plasticity and need to be further confirmed

 RhoB

Cys189, Cys192

[112]

 Rab11

Cys223, Cys224

ZDHHC3, ZDHHC7

APT1, APT2

[113]

 Rab8

–

ZDHHC2

–

[113]

 Rabin8

–

ZDHHC3, ZDHHC7

APT1, APT2

[113]

 Arc/Arg3.1

In ₉₄CLCRC₉₈ motif

–

–

[114]

 PICK1

Cys414

ZDHHC5, ZDHHC8

–

[115,116,117]

 SynDIG1

Cys191, Cys192

–

–

[118, 119]

 β2-AR

Cys265, Cys341

ZDHHC9, ZDHHC14, ZDHHC18

APT1

[120, 121]