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Table 2 Substrates of palmitoyl protein thioesterases

From: Roles of palmitoylation in structural long-term synaptic plasticity

Palmitoyl thioesterases

Substrates

APT1

G protein α-subunit [95], H-Ras [95], N-Ras [93], Synaptosomal-associated protein 23 (SNAP-23) [143], endothelial nitric-oxide synthase (eNOS) [144], BK channel [145], β2-adrenergic receptor [120], sodium-calcium (Na-Ca) exchanger 1 (NCX1) [146]

APT2

GAP-43 [98, 147], H-Ras [98], N-Ras [93], ZDHHC6 [148], Scaffolding protein Scribble (Scrib) [149]

PPT1

H-Ras [97], Cysteine string protein α (CSPα) [150], Neurospecific peptides of G proteins α subunit, GAP-43, rhodopsin and myelin glycoprotein P0 [151, 152]

PPT2

Palmitoyl-CoA [138, 153]

ABHD17

PSD-95 [96], N-Ras [91], H-Ras [96], MAP6 [142]