Fig. 4
From: The nuclear lamina is a hub for the nuclear function of Jacob
![Fig. 4](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13041-020-00722-1/MediaObjects/13041_2020_722_Fig4_HTML.png)
Basal NMDAR activity drives the synapto-nuclear messenger protein Jacob in NLS-dependent manner into the nucleus where it transiently but prominently localizes to the nuclear envelope via interaction with LaminB1. Association with the nuclear periphery is also mediated by a NES-CRM1-RanGTP dependent mechanism