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Fig. 8 | Molecular Brain

Fig. 8

From: Upregulation of Beta4 subunit of BKCa channels in the anterior cingulate cortex contributes to mechanical allodynia associated anxiety-like behaviors

Fig. 8

NS1619 enhanced the decreased PPR of ACC neurons in mCCD rats. a-b, Representative traces with an interval of 50 ms recorded in layer II/III of the ACC; a, PPR (the ratio of EPSC2 / EPSC1) were recorded at intervals of 50 ms from sham rats (n = 6 neurons in the absence or presence of paxilline (10 μM). b, PPR were recorded at intervals of 50 ms from mCCD rats (n = 8 neurons in the absence or presence of NS1619 (10 μM). c, Summary plots of PPR at intervals of 50 ms from sham and mCCD rats (n = 6 neurons for sham and n = 8 neurons for mCCD), and effects of paxilline and NS1619 on PPR of sham and mCCD rats respectively. *p < 0.05 compared with that of sham group, #p < 0.05 compared to that of mCCD group

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