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Fig. 2 | Molecular Brain

Fig. 2

From: Scopoletin ameliorates anxiety-like behaviors in complete Freund’s adjuvant-induced mouse model

Fig. 2

SP suppressed pro-inflammatory cytokine levels in the serum and BLA of CFA-injected mice. a-c SP treatment significantly reduced the elevated levels of IL-1β (a), IL-6 (b), and TNF-α (c) in the serum, as shown by ELISA. d Representative western blot analysis of IL-1β, IL-6, and TNF-α expression. Administration of SP reversed the increased expression of IL-1β (e), IL-6 (f), and TNF-α (g) normalized to β-actin. n = 6 mice from three independent experiments; **p < 0.01 versus control group; #p < 0.05, ##p < 0.01 versus vehicle group

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