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Fig. 2 | Molecular Brain

Fig. 2

From: Two novel mouse models mimicking minor deletions in 22q11.2 deletion syndrome revealed the contribution of each deleted region to psychiatric disorders

Fig. 2

Detection of DNA copy number changes and quantification of mRNA expression in the brain. a, b Array CGH profiles of chromosome 16qA13 from N1 Del(1.4 Mb)/+ (a) and Del(1.5 Mb)/+ mice (b) showing the decrease in copy number of targeting regions (pink). Array CGH data are displayed in a magnified view. c Quantitative RT-PCR analysis of mRNA from the hippocampi of WT (n = 5) and Del(1.4 Mb)/+ (n = 5) mice. d Quantitative RT-PCR analysis of WT (n = 5) and Del(1.5 Mb)/+ (n = 5) mRNA. Data are expressed as means ± SEM

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Molecular Brain

ISSN: 1756-6606