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Fig. 2 | Molecular Brain

Fig. 2

From: Ablation of interleukin-19 improves motor function in a mouse model of amyotrophic lateral sclerosis

Fig. 2

Interleukin-19 deficiency improves motor function at the late stage in the SOD1G93ATg mice. a Kaplan–Meier survival curves for SOD1G93ATg and IL-19−/−/SOD1G93ATg mice. b Kaplan–Meier curves for time to onset of SOD1G93ATg and IL-19−/−/SOD1G93ATg mice. c Body weight. Significant differences were not observed between the two types of model mice. d Rotarod test. IL-19−/−/SOD1G93ATg mice exhibited a significant improvement in motor function at the late stage (20–22 weeks) relative to SOD1G93ATg mice. Values are means ± SD (SOD1G93ATg, n = 29; IL-19−/−/SOD1G93ATg, n = 30). *, p < 0.05

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