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Fig. 4 | Molecular Brain

Fig. 4

From: Multiple synaptic connections into a single cortical pyramidal cell or interneuron in the anterior cingulate cortex of adult mice

Fig. 4

Excitatory inputs onto a single interneuron from multiple sites in the ACC. A Example mapping of a fast-spiking interneuron. The yellow star indicates the patched neuron and red circles denote channels which triggered a response in the patched neuron when stimulated. B Sample traces of action potentials recorded in fast-spiking interneurons and regular-spiking interneurons are used to determine the neuron type. C Two full trace samples comparing the typical response observed when an interneuron and pyramidal neuron are receiving an input. The additional traces represent the mapping data from (A). D Mean rise and decay time in different neuron types (PN pyramidal neuron, FS fast-spiking interneuron, RS regular-spiking interneuron) show significant difference between response kinetics for all groups (PN: n = 16 neurons/18 mice; FS: n = 5 neurons/3 mice; RS: n = 3 neurons/2 mice; ***p < 0.001 one-way ANOVA)

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Molecular Brain

ISSN: 1756-6606