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Fig. 4 | Molecular Brain

Fig. 4

From: The physiological role of Homer2a and its novel short isoform, Homer2e, in NMDA receptor-mediated apoptosis in cerebellar granule cells

Fig. 4

Overexpression of the Homer2a N-terminal domain suppressed NMDA-induced apoptosis. Normalized optical density of MTT assays of CGCs overexpressing EGFP or Homer2 constructs after the indicated NMDA treatment. NMDA-induced cell death was inhibited in H2a-N-overexpressing CGCs under all doses of NMDA. E: EGFP, F: H2a-F, C: H2a-C, N: H2a-N. *p < 0.05, one-way ANOVA and post hoc Bonferroni test; n = 3

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