Fig. 1From: Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neuronsThe Fetal Brain Clock (FBC) outperforms other DNAm clocks when applied to neurodevelopmental samples. Shown are scatterplots comparing chronological age (x-axis; days post-conception (dpc)) against predicted epigenetic age (y-axis; days post-conception) calculated using A Fetal Brain Clock (FBC), B Horvath’s Multi Tissue Clock (MTC), C Knight’s Gestational Age Clock (GAC), and D Lee’s Control Placental Clock (CPC) in our fetal brain testing dataset (n = 65, age range = 23–153 dpc). The black line indicates the identity line of chronological and predicted epigenetic age and represents a perfect prediction. Two statistics were calculated to evaluate the precision of each DNAm clock: Pearson’s correlation coefficient (r) and the root mean squared error (RMSE)Back to article page