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Fig. 7 | Molecular Brain

Fig. 7

From: Inhibition of autophagy by CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR pathway contributes to ischemic postconditioning-induced neuroprotection against cerebral ischemia-reperfusion injury

Fig. 7

ST2-104 peptide decreases the enhancement in intracellular Ca2+ induced by glutamate. Intracellular calcium ([Ca2+]i) in SH-SY5Y cells measured by flow cytometry. SH-SHY5Y cells were treated with 20 mM glutamate plus 20 μM glycine or control medium or with ST2-104 peptide for 24 h at 37 °C and then flow cytometry was performed. [Ca2+]i was measured by loading the cells with 4 μM of Fluo-3/AM and examining their fluorescence intensity. The results are presented as the mean ± SEM from three independent experiments

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Molecular Brain

ISSN: 1756-6606