Fig. 10
Effects of TPEN on the amplitudes and activation properties of IDR in the hippocampal neurons treated with Aβ25–35. a Typical example of IDR traces obtained in the hippocampal neurons (left) and record protocol (right). b Maximum current density of IDR in the different treatments. c Current voltage (I–V) curves of IDR in the different treatments. d Activation curves of IDR in the different treatments. e Half-activation potential of IDR in the different treatments. f Activation slope factor of IDR in the different treatments. The data are presented as means ± SEMs; *p < 0.05 and **p < 0.01 versus the control group; #p < 0.05 and ##p < 0.01 versus the Aβ group; n = 22 for the control group; n = 15 for the Aβ group; n = 15 for the Aβ + TPEN group. Aβ amyloid-β, IDR, outward-delayed rectifier potassium current