Fig. 9

Chemogenetic inhibition of GABAergic neurons in the ACC reduced the inhibitory presynaptic transmission. A, F The representative showed sIPSCs of PNs in ACC layer V in each group. The cumulative frequency (B, G) and amplitude (D, I) histogram of sIPSCs in different groups. The average frequency (C, H) and amplitude (E, J) of sIPSCs were statistically analyzed in each group. All data represent the mean ± SEM, n = 10 neurons from 5 rat/group. *P < 0.05, Control-hM4D(Gi) group vs Control-hM4D(Gi)-CNO group