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Fig. 8 | Molecular Brain

Fig. 8

From: Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease

Fig. 8

Enhanced presynaptic transmission in ACC. a, b Paired-pulse facilitation in ACC of PD model. a Representative traces of PPF with intervals of 50 ms. b PPF was reduced in in MPTP-treated mice compared with saline-treated mice. c–e sEPSCs recorded in the ACC of PD model. c Representative sEPSCs recorded in the ACC neuron in slices from saline-treated mice (left) and MPTP-treated mice (right). d Cumulative interevent interval (left) and amplitude (right) histograms of sEPSCs recorded in slices from saline-treated mice (black circles; n = 8 neurons) and MPTP –treated mice (red circles; n = 10 neurons). e Summary plots of sEPSC data. Averaged values of sEPSC parameters: mean peak frequency (left) and amplitude (right). **p < 0.01

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Molecular Brain

ISSN: 1756-6606