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Fig. 3 | Molecular Brain

Fig. 3

From: Molecular motor KIF3B in the prelimbic cortex constrains the consolidation of contextual fear memory

Fig. 3

KIF3B knockdown impairs the consolidation of contextual fear memory. A Timeline of the behavioral protocol with open field test on day one and contextual fear conditioning on day three. B Conditioning data, C Long-term memory test, Quantification of the freezing response to the context 24 h after fear conditioning. Student’s t test. *p < 0.05. Error bars are SEM. N = 7 per group. D Line graph depicting freezing response to the context 24 h after fear conditioning. Repeated-measures ANOVA; *p < 0.05 with Sidak post-hoc test. Error bars are SEM. N = 7 per group. Data used for preparing plots are shown in Additional file 1: Table S3. E KIF3B knockdown has no effect on short-term memory acquisition. Histogram of the freezing response during the short-term memory test performed 1 h. after contextual fear conditioning. Student’s t test. p > 0.05. Error bars are SEM. N = 8 (shScrambled) and 6 (shKIF3B). Data used for preparing plots are shown in Additional file 1: Table S3

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