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Table 1 MEF2C single nucleotide polymorphisms with Alzheimer's disease in different population

From: Progress on the roles of MEF2C in neuropsychiatric diseases

Sample

MEF2C Genotype

Phenotype

References

Caucasian population

SNPrs190982

Protective factor

[35]

Spanish population

SNPrs190982

Protective factor

[58]

Han Chinese

SNPrs190982

Effect factor on cognition

[42]

Han Chinese

SNPrs190982

No association

[66]

Alzheimer’s Research UK Consortium DNA Bank

SNPrs190982

No association

[8]

Taiwanese

SNPrs190982

No association

[41]

Taiwanese

SNPrs9293506

TC genotype had a 2.79-fold increased risk for cognitive aging compared to CC genotype

[41]

Japanese

MEF2C mRNA in leukocytes

Positively correlated with MMSE

[60]

  1. MMSE Mini-mental State Examination, SNP single nucleotide polymorphisms