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Fig. 6 | Molecular Brain

Fig. 6

From: High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression

Fig. 6

Knockdown REST inhibite the mTOR signal pathway and promoting autophagy in neurons (a) Western Blotting image of p-mTOR and mTOR in PC12 cells at sh-NC and sh-REST. (b) Detection of autophagy flux in PC12 at sh-NC and sh-REST. Data are mean ± SD. n = 3 independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Unpaired t test for (a), two-way ANOVA for (b)

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Molecular Brain

ISSN: 1756-6606