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Fig. 5 | Molecular Brain

Fig. 5

From: Silencing of hypothalamic FGF11 prevents diet-induced obesity

Fig. 5

Fgf11 knockdown in NPY/AgRP co-expressing hypothalamic cells increases CREB and decreases GSK3 activity. N41 cells were transfected with non-silencing siRNA control or siFgf11 for 48 h. A Western blots of N41 cells: transcription factors of NPY. B Quantitation of immunoblots. C Western blots of the regulators of CREB activity. D, E Quantification of immunoblots. *p < 0.05, **p < 0.01, and ***p < 0.001 (non-silencing siRNA control versus siFgf11). n = 3 or 4

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