Fig. 6
Window current of TN-associated Cav3.2 variants. a Window current of wild-type (WT) Cav3.2 illustrated by the overlap of the mean activation and inactivation curves. b-g Legend same as (a) but for TN-associated Cav3.2 variants. The dashed line depicts the window current of the WT channel for comparison. h Corresponding peak-voltage values of the window current: WT (− 51.6 mV), S187L (− 60.5 mV), A802V (− 56.8 mV), E819K (− 56.9 mV), P1120L (− 56.7 mV), P2280H (− 63.8 mV), E2291K (− 57.0 mV). i Corresponding magnitude values of the window current measured as the area under the curve: WT (2.5 a.u.), S187L (4.2 a.u.), A802V (3.1 a.u.), E819K (4.5 a.u.), P1120L (6.5 a.u.), P2280H (2.5 a.u.), E2291K (2.8 a.u.)