Fig. 5
From: Proteins secreted by brain arteriolar smooth muscle cells are instructive for neural development
Proteomic analysis of secreted proteins from mouse and human VSMCs. a KEGG pathways that were enriched after analysis 2712 MBVSMC-CM specific proteins. b Venn diagram of common and exclusive secreted proteins in MBVSMCs and HBVSMCs. Proteins with a Sum PEP Score > 1 were chosen. c KEGG pathways that were enriched after analysis 237 HBVSMC-CM specific proteins. d KEGG pathways that were enriched after analysis of 400 common proteins. e–g GO analysis of cellular components (e), molecular function (f) and biological processes (g) for 400 genes. The top ten enriched GO terms for each cluster are shown. h Protein interaction analyses of the common signaling pathway with experimentally confirmed mode (Left panel) and database prediction mode (Right panel). The ball color showed the proteins encoding genes come from different collections: VSMC-CM secretome collections (Red) and neuron transcriptome collections (Green). Line thickness indicated the strength of data support