Table 2 Differentially expressed serum metabolites between patients with SCI and healthy controls
From: The gut microbiota and metabolite profiles are altered in patients with spinal cord injury
Metabolite | Formula | Adducts | VIP | FC | p-value | Mode |
|---|---|---|---|---|---|---|
PC(18:2/0:0) | C26H50NO7P | M + H-H2O, M + Na, M + H | 1.05 | 0.99 | 0.037 | pos |
Benzyl ethyl ether | C9H12O | M + H, M + NH4, M + H-H2O | 3.71 | 1.28 | 0.004 | pos |
Hypoxanthine | C5H4N4O | M + H-H2O, M + H | 1.90 | 1.05 | 0.018 | pos |
3-Hexenoic acid | C6H10O2 | M + ACN + H, 2 M + K | 2.59 | 0.87 | 0.021 | pos |
L-Nicotianine | C10H12N2O4 | M + H-H2O | 2.79 | 0.86 | 0.009 | pos |
Indoleacetyl glutamine | C15H17N3O4 | M + H | 2.45 | 0.84 | 0.043 | pos |
Hypoglycin | C7H11NO2 | M + H | 1.12 | 1.02 | 0.002 | pos |
Pipericine | C22H41NO | M + H | 1.04 | 1.02 | 0.023 | pos |
Xestoaminol C | C14H31NO | M + H | 1.93 | 0.96 | 0.001 | pos |
12-Hydroxydodecanoic acid | C12H24O3 | 2M + NH4 | 1.40 | 0.98 | 0.000 | pos |
MG(0:0/15:0/0:0) | C18H36O4 | M + NH4 | 4.37 | 0.78 | 0.000 | pos |
6-Hydroxypentadecanedioic acid | C15H28O5 | M + ACN + H | 1.99 | 0.92 | 0.022 | pos |
DL-2-Aminooctanoic acid | C8H17NO2 | M + H | 2.23 | 0.92 | 0.004 | pos |
2-Methylbutyroylcarnitine | C12H23NO4 | M + H | 1.30 | 0.97 | 0.009 | pos |
Glycylglycylglycine | C6H11N3O4 | M + H-2H2O | 1.57 | 1.05 | 0.012 | pos |
Hydroxyprolyl-proline | C10H16N2O4 | M + H-H2O | 2.60 | 1.13 | 0.003 | pos |
Dopaquinone | C9H9NO4 | M + ACN + H | 1.61 | 0.95 | 0.017 | pos |
KOJIC ACID | C6H6O4 | M + H | 1.28 | 1.02 | 0.000 | pos |
2-Amino-4-butanoic acid | C19H25N3O7S | M + 2Na-H | 2.22 | 0.90 | 0.019 | pos |
ZAPA | C4H6N2O2S | M + H | 1.54 | 1.05 | 0.039 | pos |
Oxidanesulfonic acid | C30H28O14S | M + 2Na-H | 1.16 | 0.98 | 0.020 | pos |
13′-Carboxy-gamma-tocopherol | C28H46O4 | M-H, M + Na-2H | 1.51 | 0.96 | 0.039 | neg |
Glutamylvaline | C10H18N2O5 | M-H2O-H | 3.02 | 1.16 | 0.001 | neg |
Uridine | C9H12N2O6 | M-H | 1.16 | 1.03 | 0.049 | neg |
3b,12a-Dihydroxy-5a-cholanoic acid | C24H40O4 | M + FA-H | 2.17 | 0.91 | 0.008 | neg |
Deoxycholic acid | C24H40O4 | M-H | 1.70 | 0.94 | 0.039 | neg |
Topaquinone | C9H9NO5 | M-H2O-H | 1.54 | 1.07 | 0.046 | neg |
Allocholic acid | C24H40O5 | M-H | 2.20 | 0.92 | 0.012 | neg |
1,10-Bisaboladiene-3,4-diol | C15H26O2 | M + FA-H | 1.34 | 1.04 | 0.008 | neg |
Triptohypol F | C31H52O2 | M + FA-H | 1.39 | 0.96 | 0.043 | neg |
Malathion monocarboxylic acid | C8H15O6PS2 | M + FA-H | 1.35 | 0.96 | 0.032 | neg |
20-Dihydrodydrogesterone | C23H34 | M + Na-2H | 2.51 | 1.20 | 0.023 | neg |
7a,17-dimethyl-5b-Androstane- | C21H36O2 | M + FA-H | 1.45 | 0.96 | 0.046 | neg |
3a,17b-diol | Â | Â | Â | Â | Â | Â |
Taurochenodeoxycholate-7-sulfate | C26H45NO9S2 | M-2H | 2.54 | 1.10 | 0.000 | neg |
Acetyl-DL-Valine | C7H13NO3 | M-H | 1.08 | 1.03 | 0.036 | neg |
Hydantoin-5-propionic acid | C6H8N2O4 | M-H | 2.00 | 0.92 | 0.009 | neg |
Asparaginyl-hydroxyproline | C9H15N3O5 | M + FA-H | 6.25 | 0.53 | 0.001 | neg |
Gamma-D-glutamylglycine | C7H12N2O5 | M-H | 1.47 | 0.97 | 0.001 | neg |
D-Apiose | C5H10O5 | M-H | 1.75 | 1.07 | 0.020 | neg |
Hexadecanedioic acid | C16H30O4 | M-H | 1.61 | 1.05 | 0.002 | neg |
L-Glutamate | C5H9NO4 | M-H | 1.04 | 1.02 | 0.048 | neg |