Fig. 5

Sag voltage was altered after LTD-IE induction. A R_in was not altered in wild-type. B Sag voltage at the 1 h time point was significantly lower than the sham and the 4 h time point (sham vs. 1 h, F _{1, 28} = 4.50, p = 0.043; 1 h vs. 4 h, F _{1, 25} = 4.31, p = 0.048). C R_in was not significantly altered in STIM1^PKO, although there was elevation at the 1 h time point (sham vs. 1 h, F _{1, 26} = 4.06, p = 0.054). (D) There were no significant changes in sag voltage through time. Sample numbers of wild-type (sham n = 18, 1 h n = 12, 4 h n = 15, 24 h n = 21) and STIM1.^PKO (sham n = 14, 1 h n = 14, 4 h n = 14, 24 h n = 9) are the same for all panels. Two-way ANOVA was used for all panels. The graphs are shown as mean ± SEM. *p < 0.05